AB1799-HPR COMPARISON OF EXERCISE CAPACITY, PHYSICAL ACTIVITY LEVEL, AND PERIPHERAL MUSCLE STRENGTH IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS WITH HEALTHY INDIVIDUALS

Background Systemic lupus erythematosus (SLE) is a chronic, autoimmune, inflammatory rheumatic disease that causes tissue damage through autoantibodies and immune complexes. Patients with chronic diseases such as SLE fall into vicious circle. Fatigue depression can negatively affect the quality of life cause patients to stay at home hence, be physical inactivity. As result inactivity; exercise capacity muscle strength decrease. Objectives The aim this study investigate activity, peripheral strength, capacity, sleep, fatigue, anxiety, levels between healthy individuals. Methods Twenty-six (32.5 (24.75/43.25) years) 29 individuals (30 (23/32) were compared. Exercise (6-minute walk test (6MWT)), (dynamometer), activity (the Xiaomi Mi Band 4 smart bracelet device), fatigue (Fatigue Severity Scale (FSS)), anxiety (Hospital Anxiety Depression scale (HAD)), (SLE-specific QOL (SLEQoL)), sleep (Pittsburgh Sleep Quality Index (PSQI)) assessed. Results Demographic characteristics similar in both groups except for cigarette consumption (pack*years) (p>0.05). 6MWT distance, level, SLEQoL, PSQI scores significantly lower; FSS HAD higher (p<0.05). Moreover; difference post pretest values heart rate, dyspnea, quadriceps femoris was compared Conclusion had lower life, quality, depression. In addition; These physically inactive. Further studies are needed effects efficiency these symptoms on SLE. References [1] Karim MY, Miranda LC, Tench CM, Gordon PA, D’Cruz DP, Khamasthta MA, Hughes GRV (2002) Presentation prognosis shrinking lung syndrome systemic erythematosus. Semin Artrhitis Rheum 31:289–298. [2] Bertsias G, Ioannidis JP, Boletis J, Bombardieri S, Cervera R, Dostal C, et al. EULAR recommendations management Report Task Force Standing Committee International Clinical Studies Including Therapeutics. Ann Dis 2008;67(2):195–205. [3] Ana J. Pinto, Cintia N. H. Miyake, Fabiana B. Benatti, Clovis A. Silva, Adriana M. E. Sallum, Eduardo Borba, L. De S_ A-Pinto, Eloisa Bonf A, Bruno Gualano. Reduced Aerobic Capacity Life Physically Inactive With Lupus Erythematosus Mild or Disease Arthritis Care & Research Vol. 68, No. 12, December 2016, pp 1780–1786. Acknowledgements: NIL. Disclosure Interests None Declared.